I have found a great script to remove local profile to a remote or a local machine. I have added two features to this script :

• list only the “non loaded” profile
• possibility to remove all profiles

The first point is important because if you try to delete a loaded local profile (local or remote), the script will fail.
The second point allow you to delete in one shot all local profiles listed in the target computer.

Have fun…

My Powershell script categories

• Active Directory
• Cluster
• Database
• Exchange
• Files and folders
• Hardware
• Network
• Operating System
• PKI
• SCCM
• Service and process
• Tips
• VMWare

<#   
.SYNOPSIS   
    Interactive menu that allows a user to connect to a local or remote computer and remove a local profile. 
.DESCRIPTION 
    Presents an interactive menu for user to first make a connection to a remote or local machine.  After making connection to the machine,  
    the user is presented with all of the local profiles and then is asked to make a selection of which profile to delete. This is only valid 
    on Windows Vista OS and above for clients and Windows 2008 and above for server OS.    
.NOTES   
    Name: Remove-LocalProfile 
    Author: Boe Prox 
    DateCreated: 26JAN2011 
    Contributor: Nicolas HAHANG      
    DateModified: 14JAN2016
.LINK   
    http://boeprox.wordpress.com
    http://msdn.microsoft.com/en-us/library/ee886409%28v=vs.85%29.aspx 
.EXAMPLE  
Remove-LocalProfile 
 
Description 
----------- 
Presents a text based menu for the user to interactively remove a local profile on local or remote machine.    
#>  
 
#Prompt for a computer to connect to 
$computer = Read-Host "Please enter a computer name" 
#Test network connection before making connection 
If ($computer -ne $Env:Computername) { 
    If (!(Test-Connection -comp $computer -count 1 -quiet)) { 
        Write-Warning "$computer is not accessible, please try a different computer or verify it is powered on." 
        Break 
        } 
    } 
Try {     
    #Verify that the OS Version is 6.0 and above, otherwise the script will fail 
    If ((Get-WmiObject -ComputerName $computer Win32_OperatingSystem -ea stop).Version -lt 6.0) { 
        Write-Warning "The Operating System of the computer is not supported.`nClient: Vista and above`nServer: Windows 2008 and above." 
        Break 
        } 
    } 
Catch { 
    Write-Warning "$($error[0])" 
    Break 
    }     
Do {     
#Gather all of the user profiles on computer 
Try { 
	# ADDED BY NH
    # $users = Get-WmiObject -ComputerName $computer Win32_UserProfile -filter "LocalPath Like 'C:\\Users\\%'" -ea stop 
	$users = Get-WmiObject -ComputerName $computer Win32_UserProfile -filter "LocalPath Like 'C:\\Users\\%' and Loaded='False'" -ea stop 
    } 
Catch { 
    Write-Warning "$($error[0]) " 
    Break 
    }     
	
#Cache the number of users 
$num_users = $users.count 
 
Write-Host -ForegroundColor Green "User profiles on $($computer):" 
 
    #Begin iterating through all of the accounts to display 
    For ($i=0;$i -lt $num_users; $i++) { 
        Write-Host -ForegroundColor Green "$($i): $(($users[$i].localpath).replace('C:\Users\',''))" 
        } 
    Write-Host "-----" 
    Write-Host -ForegroundColor Green "all: Remove all local profiles listed above" 
    Write-Host -ForegroundColor Green "q: Quit" 
    #Prompt for user to select a profile to remove from computer 
    Do {     
		# ADDED BY NH
        # $account = Read-Host "Select a number to delete local profile or 'q' to quit" 
		$account = Read-Host "Select a number to delete local profile or type 'ALL' to delete them all. Type 'q' to quit" 
        #Find out if user selected to quit, otherwise answer is an integer 
		# ADDED BY NH
        # If ($account -NotLike "q*") { 
        If ($account -Notmatch "all|q") { 
			$account = $account -as [int] 
            } 
        }         
    #Ensure that the selection is a number and within the valid range 
    Until (($account -lt $num_users -AND $account -match "\d") -OR $account -Like "q*" -or $account -match "all") 
    If ($account -Like "q*") { 
        Break 
        } 
	
	# ADDED BY NH
	if ($account -is [int]){
    Write-Host -ForegroundColor Yellow "Deleting profile: $(($users[$account].localpath).replace('C:\Users\',''))" 
    #Remove the local profile 
    ($users[$account]).Delete() 
    Write-Host -ForegroundColor Green "Profile:  $(($users[$account].localpath).replace('C:\Users\','')) has been deleted" 
 
    #Configure yes choice 
    $yes = New-Object System.Management.Automation.Host.ChoiceDescription "&Yes","Remove another profile." 
 
    #Configure no choice 
    $no = New-Object System.Management.Automation.Host.ChoiceDescription "&No","Quit profile removal" 
 
    #Determine Values for Choice 
    $choice = [System.Management.Automation.Host.ChoiceDescription[]] @($yes,$no) 
 
    #Determine Default Selection 
    [int]$default = 0 
 
    #Present choice option to user 
    $userchoice = $host.ui.PromptforChoice("Information","Remove Another Profile?",$choice,$default) 
		}

	# ADDED BY NH
	# Remove all local profiles
	if ($account -match "all"){
		Write-Host "enter all"
		Write-Host $num_users
		for ($j=($num_users -1); $j -ge 0; $j--) { 
			Write-Host -ForegroundColor Green "$($j): $(($users[$j].localpath).replace('C:\Users\',''))" 
			
			#Remove the local profile 
		    ($users[$j]).Delete() 
		    Write-Host -ForegroundColor Green "Profile:  $(($users[$j].localpath).replace('C:\Users\','')) has been deleted" 
    	    }
	    #Present choice option to user 
	    $userchoice = 1
		}
	} 
#If user selects No, then quit the script     
Until ($userchoice -eq 1)

Reference

Source